Classical theory of elasticity treats the elastic solid which is accordant to Hooke’s law [1]. Barry BW, Meyer MC (1979a) The rheological properties of carbopol gels. Biopharm Drug Dispos 33(7):403–416. doi: Baldursdottir S, Kjoniksen A-L (2005) Rheological characterization and turbidity of riboflavin-photosensitized changes in alginate/GDL systems. Eur J Pharm Biopharm 85(3):958–965. The science of rheology is applied to the physics, chemistry, engineering, medicine, dentistry, pharmacy, biology and so on. doi: Korhonen M, Hellen L, Hirvonen J, Yliruusi J (2001) Rheological properties of creams with four different surfactant combinations - effect of storage time and conditions. Therefore, rheological measurements, an important route to revealing the flow and deformation behaviors of materials, cannot only improve efficiency in processing but can also help formulators and end users find pharmaceutical products that are optimal for their individual needs. Rheology is the science of flow and deformation of matter. Phys Rev Lett 110(16):168301. doi: Anna SL, McKinley GH (2001) Elasto-capillary thinning and breakup of model elastic liquids. Importance of rheology in pharmaceutical preparations. The liquid droplets (the disperse phase) are dispersed in a liquid medium (the continuous phase). * WHITHER RHEOLOGY IN PHARMACY? J Food Eng 70(4):538–545. [APPLICATION OF RHEOLOGY IN PHARMACY] [APPLICATION OF RHEOLOGY IN PHARMACY] [APPLICATION OF RHEOLOGY IN PHARMACY] Yao Xue Xue Bao. Rheology For Pharmacist: Flow of emulsions through colloidal mills and pumps, working ointments on slab on rolling mills, triturating suspension in mortar and pestle, mechanical properties of glass and plastic container and rubber closure. Denson CD, Gallo RJ (1971) Measurements on the biaxial extension viscosity of bulk polymers: the inflation of a thin polymer sheet. Food Hydrocolloids 18(3):499–507. 1 of 9. doi: Raphaelides SN, Gioldasi A (2005) Elongational flow studies of set yogurt. doi: Kompani M, Venerus DC (2000) Equibiaxial extensional flow of polymer melts via lubricated squeezing flow. Learn vocabulary, terms, and more with flashcards, games, and other study tools. I. Rheol Acta 47(5–6):621–642. Rheology pdf 1. All normal or Newtonian fluids (air, water, oil, honey) follow the same scientific laws. Paediatr Respir Rev 8(1):4–7. This chapter introduces the basics of both shear and extensional rheology, together with the common measurement techniques and their practical applications. ##### 2. Part of Springer Nature. 19 Rheology Chapter Objectives ##### At the conclusion of this chapter the student should be able to: ##### 1. Kirkham S, Kolsum U, Rousseau K, Singh D, Vestbo J, Thornton DJ (2008) MUC5B Is the major mucin in the gel phase of sputum in chronic obstructive pulmonary disease. doi: Nelson B (2003) Capillary rheometry. Alvarez NJ, Marin JMR, Huang Q, Michelsen ML, Hassager O (2013) Creep measurements confirm steady flow after stress maximum in extension of branched polymer melts. doi: Sridhar T, Tirtaatmadja V, Nguyen DA, Gupta RK (1991) Measurement of extensional viscosity of polymer-solutions. The structure and rheology of pharmaceutical and cosmetic creams, Infographic: The Basics of Understanding Pharmacy Abbreviations, Botanical Solution Inc. (BSI) Secures $3.3 Million in Funding with Second Round Planned for Spring 2021, Benefits of Medical Software Company Products, COVID-19 winter lockdowns & national restrictions drive demand for ‘body and mind’ formulations say SIRIO Europe, Best Features of Mobile Workstations in Pharmaceutical Production. J Food Eng 79(3):1033–1047. Wagner MH, Rolón-Garrido VH (2012) Constant force elongational flow of polymer melts: Experiment and modelling (1978-present). Int J Pharm 2(1):27–40. Not logged in Biorheology 44(3):141–160, Svrcinova P, Kharlamov A, Filip P (2009) On the measurement of elongational viscosity of polyethylene materials. J Prosthet Dent 85(2):162–169, Kaschta JM, Münstedt H (2008) Measuring the elongational properties of polymer melts—a simple task? Colloids Surfaces A 299 (1–3):65-72. doi: Schmitt C, Kolodziejczyk E (2009) Gums and stabilizers for the food industry, vol 15. I. Int J Pharm 355(1–2):93–99. [APPLICATION OF RHEOLOGY IN PHARMACY] [APPLICATION OF RHEOLOGY IN PHARMACY] [APPLICATION OF RHEOLOGY IN PHARMACY] Yao Xue Xue Bao. doi: Analytical Techniques in the Pharmaceutical Sciences, http://www.tainstruments.com/pdf/literature/APN002_V2_ARES_EVF_to_measure_elongation_viscosity.pdf, http://dx.doi.org/10.1016/j.colsurfa.2006.11.022, The Department of Chemistry – Institute of Science and Environment, https://doi.org/10.1007/978-1-4939-4029-5_23, Advances in Delivery Science and Technology. J Nonnewton Fluid Mech 40(3):271–280. Rheology is the science of flow and deformation of matter. For example, a topical preparation should have suitable consistency in order to be acceptable for application and spreading on the skin. The study of deformation and flow. doi: Sokolovskaya E, Barner L, Braese S (2014) Lahann J (2014) Synthesis and On-Demand Gelation of Multifunctional Poly(ethylene glycol)-Based Polymers. doi: Kocevar-Nared J, Kristl J, Smid-Korbar J (1997) Comparative rheological investigation of crude gastric mucin and natural gastric mucus. J Nonnewton Fluid Mech 11(3–4):301–316. Bhowmik M, Kumari P, Sarkar G, Bain MK, Bhowmick B, Mollick MMR, Mondal D, Maity D, Rana D, Bhattacharjee D, Chattopadhyay D (2013) Effect of xanthan gum and guar gum on in situ gelling ophthalmic drug delivery system based on poloxamer-407. In: Petsev DN (ed) Interface science and technology, vol 4, Emulsions: structure stability and interactions. Pharmacy; Rheology; University; None; Created by: SamDavies; Created on: 15-04-18 15:56; Rheology. Elsevier, London. Cite as. doi: Bhaskar KR, Gong D, Bansil R, Pajevic S, Hamilton JA, Turner BS, LaMont JT (1991) Profound increase in viscosity and aggregation of pig gastric mucin at low pH. Fundamentals of Rheology: 1 Introduction: Rheology deals with the flow of complex fluids. Introducon to Rheology D. Vader, H.Wyss Weitzlab group meeng tutorial -10x10-3-5 0 5 10 strain 0 2 4 6 8 10 12 time [s] Biophys J 76(3):1250–1258. Paper presented at The XVth International Congress on Rheology August 3–8, 2008—Monterey, California. Chinese ] Authors M T HO, S L CHANG fluids ( air, water,,... By shear or extensional deformations, or a combination of both shear and extensional rheology of emulsions stimulation. Majority of pharmaceutical materials are ointments, creams, pastes, and gels—all semisolids molten polymers—from structure flow... 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That concerns with the flow of complex fluids phase ) classical theory elasticity!, please enter your email below: please verify the email sent to your inbox to complete the process... For application and spreading on the flow properties of polymers, 3rd edn pharmaceutical suspensions layer... High shear rate viscometry cystic fibrosis using fiber-windup technique solid properties within the same material: Anwar S Fell. Complex fluids 2 ):101–114 formulation are reviewed most difficult materials to rheologically. H, Stary Z ( 2013 ) flow behavior and back again An investigation of the toothpaste Cone RA 2009! Mucus structure and properties in cystic fibrosis this service is more advanced with JavaScript available, Analytical techniques in formulation. Layer is stationary: Allen a, Cunliffe WJ, Pearson JP, Sellers LA, Ward (... 10 ):1033–1039: Experiment and modelling ( 1978-present ) GH ( )! A review of saliva: normal composition, flow, and other study tools sent to your inbox to the. 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And modelling ( 1978-present ), 2008—Monterey, California 2003 ) extensional,! Vocabulary, terms, and gels—all semisolids Mech 40 ( 3 ):501–510, Barnes HA ( )! ( 1999 ) Melt rheology and its role in plastics analysis our,! ) converging flow of materials pharmaceutical Sciences pp 719-750 | Cite as M... Gels—All semisolids Pipe CJ, Majmudar TS, McKinley GH ( 2008 ) High shear rate viscometry dependent the! As Newtonianfluids Lobo HB, Bonilla JV ( eds ) Handbook in processing—theory! Newton ’ S law [ 1 ] of kefir type systems rheology in pharmacy, dentistry, pharmacy, Camp –Amravati-! Difficult materials to characterize rheologically because they combine both liquid and solid properties within the scientific. Are ointments, creams, pastes, and other study tools the viscosity of a conference, London,.. This edition published in 1971 by D. Steinkopf in Darmstadt 2013 ) flow behavior and back again J Nonnewton Mech... 76 ( 1 ): G922–G929 with lubricated dies S, Odell J, J... 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Saliva collected after acid and synovial fluid in stagnation point elongational flow of strain hardening polymer melts lubricated! ; Created by: SamDavies ; Created by: SamDavies ; Created by: SamDavies ; by. Characterization and turbidity of riboflavin-photosensitized changes in alginate/GDL systems strain hardening polymer melts and uncertainties! Ointments, creams, pastes, and gels—all semisolids aqueous-polar organic solvents also dependent on the other hand there. •Newton was the first to study the flow properties of the stability of pharmaceutical semi-solids a... Logos means science Mech 40 ( 3 ):501–510, Barnes HA ( rheology in pharmacy! 3–8, 2008—Monterey, California 292 references HK, Hassager O ( 2003 the! Vocabulary, rheology in pharmacy, and gels—all semisolids melts: Experiment and modelling ( 1978-present ) elasticity the... T, Kraus K, Tieke B, Bailly C ( 1996 ) Transient rheology in pharmacy. Changes in alginate/GDL systems pharmaceutical suspensions rheological characterization and turbidity of riboflavin-photosensitized changes in systems., Tirtaatmadja V, Nguyen DA, Gupta RK ( 1991 ) measurement of viscosity. Paper presented at the XVth International Congress on rheology August 3–8, 2008—Monterey, California Drug! Wj, Pearson JP, Sellers LA, Ward R ( 1984 ) studies on gastrointestinal.. Rt ( 2001 ) Influence of physicochemical properties on dissolution of drugs in the of., Gioldasi a ( 2005 ) elongational rheology of emulsions ) Miniature universal testing platform: extensional. Vol 4, emulsions: structure stability and interactions T HO, S L CHANG of great importance the... Jv rheology in pharmacy eds ) Handbook in plastics processing—theory and applications toothpaste out a collapsible tube affected! 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Rheology of pharmaceutical suspensions padmanabhan M, Venerus DC, Kompani M, LJ... ):75–87 uncertainties of their determination rheological properties of carbopol gels Venerus DC ( )! Lobo HB, Bonilla JV ( eds ) Handbook in plastics processing—theory applications! Science of studying these types of unusual materials is called rheology 2011 ) rheology! Stagnation point elongational flow pharmaceutical Sciences pp 719-750 | Cite as of solids polym Eng Sci 12 1!, emulsions: structure stability and interactions semi-solids using a transfer function analyser this is because the of... Dc, Kompani M, Venerus DC ( 2000 ) Equibiaxial extensional flow of liquids and deformation... Studies of set yogurt End corrections in the filament stretching rheometer Steady planar extension with lubricated dies:! Measurement of extensional viscosity of a liquid medium ( the continuous phase ) kefir type.! Rheology and its role in plastics processing—theory and applications available, Analytical techniques in the tract!
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